產(chǎn)品英文名稱(chēng)：WNT-3a, Human
產(chǎn)品中文名稱(chēng)：人重組WNT-3a蛋白

人重組WNT-3a蛋白 產(chǎn)品簡(jiǎn)介：
StemRD已研發(fā)出一種新穎的表達(dá)和純化諸如WNT蛋白等“困難”蛋白的先進(jìn)方法。我們獨(dú)特的處理方法能得到純度和活性均領(lǐng)先于市場(chǎng)方法生產(chǎn)的WNT蛋白。StemRD的WNT蛋白絕不含有現(xiàn)今市場(chǎng)普遍使用的WNT蛋白中含有的某些非特異性成分。
WNT-3a 是WNT 信號(hào)蛋白家庭的成員之一，在胚胎成長(zhǎng)和成體組織維護(hù)方面起關(guān)鍵作用。WNT-3a 是典型的通過(guò)β-聯(lián)蛋白通路發(fā)送信號(hào)。已有規(guī)格的WNT-3a是一個(gè)包含328個(gè)氨基酸殘基的單鏈蛋白質(zhì)。由于糖基化，WNT-3a 在非還原條件下用SDS-PAGE處理會(huì)明顯損失掉38-41 kDa分子量。StemRD公司生產(chǎn)的WNT-3a是用人體細(xì)胞系中Wnt-3a cDNA 在無(wú)蛋白培養(yǎng)基上過(guò)度表達(dá)得到。使用特有的純化方法，區(qū)別于其它已發(fā)表的純化方法，提高蛋白純度。

人重組WNT-3a蛋白 產(chǎn)品特性：
? WNT-3a使用LC/MS 層析，純度大于98%，結(jié)構(gòu)經(jīng)過(guò)NMR驗(yàn)證
? 生物活性認(rèn)證：經(jīng)過(guò)生物試驗(yàn)驗(yàn)證，優(yōu)于其它同類(lèi)型產(chǎn)品
? WNT-3a 是典型的通過(guò)β-聯(lián)蛋白通路發(fā)送信號(hào)
? 僅限用于科學(xué)研究，非人體使用

WNT-3a, Human 產(chǎn)品英文簡(jiǎn)述：
We express and purify WNT proteins by using a proprietary process that is distinctive from the published protocol. Our method results in WNT proteins that are purer and more active than market-leading products which have been associated with non-specific artifacts.
WNT-3a is a member of the WNT family of signaling proteins that play key roles in embryonic development and the maintenance of adult tissues. WNT-3a is a prototypic canonical WNT that signals through the β-catenin pathway. The predicted size of human WNT-3a is a monomeric protein containing 328 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of 38 – 41 kDa on SDS-PAGE under non-reducing conditions. StemRD’s WNT-3a is produced from a human cell line overexpressing human Wnt-3a cDNA in protein-free medium. Purification is done by a proprietary process that is distinct from the published method.

WNT all compounds are:
1. >98% pure by LC/MS analysis, and structurally verified by NMR.
2. Bioactivity Certified: tested for biological activities, an advent-age over other supplies.