Phc2 antibody (mAb)
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產(chǎn)品英文名稱:Phc2 antibody (mAb)
產(chǎn)品中文名稱:Phc2 抗體 (mAb)
Active Motif Phc2 抗體 (mAb)產(chǎn)品英文描述:
Background
Phc2, polyhomeotic homolog 2 (also known as EDR2, early development regulatory protein 2) is a component of the polycomb group (PcG) multiprotein PRC1 complex. The PRC1 complex is required to maintain the stable repression of the Hox genes during development. This chromatin-associated protein complex acts via chromatin remodeling and histone modifications. Phc2 has been shown to interact with PHC1, BMI1, MAPKAPK2 and MCRS1.
Immunogen
This Phc2 antibody was raised against a recombinant fragment of human Phc2.
Application Notes
This Phc2 antibody has been validated for use in the following applications:
ChIP: see reference 1
IF: see reference 2
IP: see reference 1
References
1. Isono, K. et. al. (2005) Mol. Cell. Bio. 25: 6694-6706.
2. Takada, Y. et. al. (2007) Development 134: 579-590.
Buffer
Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Storage
Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Guarantee
This product is guaranteed for 6 months from date of receipt.
This product is for research use only and is not for use in diagnostic procedures.
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