產(chǎn)品英文名稱:A83-01
產(chǎn)品中文名稱:A83-01

A83-01 產(chǎn)品英文簡(jiǎn)述:
A selective inhibitor of ALK-4 (Activin/Nodal receptor), ALK-5 (TGF-β type I receptor), and ALK-7 (nodal receptor). Only weakly inhibits ALK-1, -2, -3, and -6. 3-(6-METHYLPYRIDIN-2-YL)-1-PHENYLTHIOCARBAMOYL-4-QUINOLIN-4-YLPYRAZOLE
 
Ref: Tojo, M., et al. The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta. Cancer Sci. 96: 791-800, 2005.
 
Purity: Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: Not determined.