免费国产一区2区3区4区_日韩精品一区二区AV免费_日本色网片在线观看_国产三级经典户外_色资源av中文无码先锋剧情_女生麻豆av在线_亚洲色婷婷久久99精品_精品视频在线无码免费_波多野结衣一区二区网页_亚洲一级片中文字幕

當(dāng)前位置:

產(chǎn)品編號(hào):HY-001130

ProSpec Recombinant Human Interleukin-4 CHO 【IL 4 CHO】重組人白介素-4,CHO表達(dá)

Recombinant Human Interleukin-4 CHO

促銷優(yōu)惠 本商品正在參加促銷活動(dòng),價(jià)格 -

規(guī)格:

-

數(shù)量:

價(jià)格:

¥-

折后價(jià):

¥-

金牌價(jià)格:

¥-
  • 注冊(cè)品牌:
  • 生產(chǎn)廠家: ProSpec
  • 訂購(gòu)貨號(hào):
  • 保存溫度: -18℃
  • 規(guī)格型號(hào): 2ug,10ug,1mg
  • 產(chǎn)品編號(hào): HY-001130
  • 產(chǎn)品種類: 特定細(xì)胞專用培養(yǎng)基

到貨時(shí)間:上海倉(cāng)庫(kù)有現(xiàn)貨,2~5天到貨

聯(lián)系客服:

客服電話 150 2101 0459

產(chǎn)品描述 說明書【下載】 用戶評(píng)論【0】

英文名稱:ecombinant Human Interleukin-4 CHO
中問簡(jiǎn)稱:【IL 4 CHO】重組人白介素-4,CHO表達(dá)

 

Recombinant Human Interleukin-4 CHO 【IL 4 CHO】重組人白介素-4,CHO表達(dá) 細(xì)胞因子描述:

IL4是多向性的激活T細(xì)胞產(chǎn)生的細(xì)胞因子。IL4是白介素4受體的配體。IL13白介素4受體也綁定,這可能導(dǎo)致許多重疊的細(xì)胞因子和IL13功能。STAT6、傳感器信號(hào)和轉(zhuǎn)錄激活劑,已被證明在介導(dǎo)免疫中發(fā)揮核心作用的監(jiān)管這一細(xì)胞因子的信號(hào)。這種基因,IL3 IL5、IL13 CSF2形成一個(gè)細(xì)胞因子基因簇5號(hào)染色體上q,特別是接近IL13基因。IL4,IL13 IL5發(fā)現(xiàn)監(jiān)管協(xié)調(diào)由幾個(gè)遠(yuǎn)程監(jiān)管元素在染色體上的120多千堿基范圍。兩個(gè)或者拼接成績(jī)單變異的基因編碼已報(bào)告不同的亞型。
人白介素-4,CHO表達(dá)重組蛋白是在CHO中國(guó)倉(cāng)鼠卵巢細(xì)胞中重組表達(dá)的,是一條單鏈、非糖基化的多肽鏈,包含有129個(gè)氨基酸,分子量為14kDa,由于糖基化而導(dǎo)致在SDS-PAGE電泳顯示分子量為18 kDa。該人白介素-4,CHO表達(dá)重組蛋白最終由標(biāo)準(zhǔn)的色譜技術(shù)純化出。
來源宿主---CHO中國(guó)倉(cāng)鼠卵巢細(xì)胞中重組表達(dá)。

 

Recombinant Human Interleukin-4 CHO 【IL 4 CHO】重組人白介素-4,CHO表達(dá) 細(xì)胞因子使用須知:

溶解:提供的人白介素-4,CHO表達(dá)(IL 4 CHO)產(chǎn)品為過濾滅菌的白色凍干粉末;該凍干粉末是從含人白介素-4,CHO表達(dá)(IL 4 CHO)的磷酸鹽緩沖鹽水(pH 7.4)中凍干產(chǎn)生的。我們建議加無(wú)菌的18MΩ-cm水以配制工作儲(chǔ)存液到100ug/ml,后繼實(shí)驗(yàn)過程中可根據(jù)實(shí)驗(yàn)要求進(jìn)一步稀釋。
保存:人白介素-4,CHO表達(dá)(IL 4 CHO)凍干粉末在室溫可保存3周,或置于-18℃凍存用于長(zhǎng)期保存。重新溶解后可以在4℃冷藏保存至少2-7天;如果想延長(zhǎng)保存時(shí)間,建議分裝(加載體蛋白如0.1% HSA或 BSA)后置于-18℃凍存。請(qǐng)避免反復(fù)凍融。

 

Recombinant Human Interleukin-4 CHO 【IL 4 CHO】重組人白介素-4,CHO表達(dá) 細(xì)胞因子英文描述:

Synonyms 

BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra.


Introductionn 

IL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.


Description 

Interleukin-4 Human Recombinant produced in CHO is a single, non-glycosylated polypeptide chain containing 129 amino acids and having a molecular mass of 14 kDa, the glycosilation of IL-4 migrates as 18 kDa on SDS-PAGE.
The IL-4 is purified by proprietary chromatographic techniques.


Source 

Chinese Hamster Ovarian Cells.


Physical Appearance
  (外觀)

Sterile Filtered White lyophilized (freeze-dried) powder.


Formulation 

Lyophilized from a Phosphate- Buffered Saline (pH 7.4).


Solubility  (溶解性)

It is recommended to reconstitute the lyophilized Interleukin-4 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.


Stability     (穩(wěn)定性)

Lyophilized Interleukin-4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL4 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.


Purity     (純度)

Greater than 97.0% as determined by

(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.


Biological Activity   (生物活性)

Measured in a cell proliferation assay using TF-1 cells. The ED50 for this effect is 0.05-0.2ng/ml corresponding to a Specific Activity of 5,000,000-20,000,000IU/mg.

說明書【下載】

暫無(wú)說明書

用戶評(píng)論【0】

購(gòu)買ProSpec Recombinant Human Interleukin-4 CHO 【IL 4 CHO】重組人白介素-4,CHO表達(dá)的用戶評(píng)論如下:
暫無(wú)評(píng)論
如果您對(duì)生產(chǎn)廠家 ProSpec,

ProSpec Recombinant Human Interleukin-4 CHO 【IL 4 CHO】重組人白介素-4,CHO表達(dá)

感興趣,歡迎添加QQ微信為好友進(jìn)行咨詢,您也可以撥打客服電話進(jìn)行人工咨詢。

瀏覽記錄

暫無(wú)瀏覽記錄