Recombinant Human FGF-basic
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產(chǎn)品英文名稱:PeproTech 100-18B Recombinant Human FGF-basic,500ug
產(chǎn)品中文名稱:PeproTech 100-18B 人重組bFGF干細(xì)胞生長(zhǎng)因子,500ug
PeproTech 100-18B Recombinant Human FGF-basic,500ug 產(chǎn)品簡(jiǎn)介
FGF-basic 又稱FGF-2, HBGF-2, Prostatropin,它是23種已知FGF家族成員之一。FGF家族蛋白在胚胎發(fā)育和胚后生長(zhǎng)及組織再生方面發(fā)揮重要作用,可促進(jìn)細(xì)胞增殖和分化。FGF-basic是一個(gè)非糖基化肝素結(jié)合生長(zhǎng)因子,在腦、垂體、腎、視網(wǎng)膜、骨、睪丸、腎上腺肝、單核細(xì)胞、薄壁分泌細(xì)胞和內(nèi)皮細(xì)胞中表達(dá)。FGF-basic通過FGFR 1b, 1c, 2c, 3c和4進(jìn)行信號(hào)表達(dá)。重組人成纖維細(xì)胞生長(zhǎng)因子(FGF-basic)分子量為17.2 kDa,含有154個(gè)氨基酸殘基。使用無動(dòng)物源試劑制造。無動(dòng)物源成份。只作科研應(yīng)用(RUO)。
PeproTech 100-18B Recombinant Human FGF-basic,500ug 同義詞
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
PeproTech 100-18B 人重組bFGF干細(xì)胞生長(zhǎng)因子,500ug 氨基酸序列
AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL
RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR
YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT
SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
PeproTech 100-18B Recombinant Human FGF-basic,500ug 來源: E.coli
PeproTech 100-18B Recombinant Human FGF-basic,500ug 純度:Greater than 95% by SDS-PAGE gel and HPLC analyses.
PeproTech 100-18B Recombinant Human FGF-basic,500ug 生物活性:The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
PeproTech 100-18B Recombinant Human FGF-basic,500ug 交叉反應(yīng):Cow, Dog, Frog, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Human + Mouse, Rat + Chicken, Human, Horse, Bacteria, Trout, Chicken, Human + Rat, Leech, N/A, Human + Virus
PeproTech 100-18B 人重組bFGF干細(xì)胞生長(zhǎng)因子,500ug 研究方向
血管再生/心血管, 細(xì)胞培養(yǎng), FGF超家族, 炎癥, 神經(jīng)生物學(xué), 增殖, 干細(xì)胞&分化, 傷口愈合
PeproTech 100-18B Recombinant Human FGF-basic,500ug 英文描述
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.
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